Diagnostic strategies for unknown primary cancer
نویسندگان
چکیده
منابع مشابه
Cancer of unknown primary
Cancer of unknown primary (CUP) ranges within top 10 cancers in both incidence and mortality. As primary identification is crucial to choosing treatment, guidelines on CUP emphasize the diagnostic strategy. Whether guidelines are complied with, or if they are indeed helpful, is however unclear. We compared procedures performed in suspected CUP patients with recommendations of national guideline...
متن کاملCancer of unknown primary site.
Copyright © 2014 Massachusetts Medical Society Cancer of unknown primary site is a heterogeneous group of cancers for which the anatomical site of origin remains occult after detailed investigations.1,2 The emergence of sophisticated imaging, immunohistochemical testing, and molecular-profiling tools has influenced our approach to unknown primary cancer, although it has also increased the ambig...
متن کاملCancer of Unknown Primary Origin.
About 3% of all cancer patients suffer from cancer of unknown primary origin. These patients present with metastatic disease for which a primary site cannot be detected at the time of diagnosis. Sophisticated diagnostic techniques and operational procedures have failed to improve the diagnostic efficacy in this group of patients. Consequently, a limited diagnostic procedure with basic laborator...
متن کاملA Microarray-Based Gene Expression Analysis to Identify Diagnostic Biomarkers for Unknown Primary Cancer
BACKGROUND The biological basis for cancer of unknown primary (CUP) at the molecular level remains largely unknown, with no evidence of whether a common biological entity exists. Here, we assessed the possibility of identifying a common diagnostic biomarker for CUP using a microarray gene expression analysis. METHODS Tumor mRNA samples from 60 patients with CUP were analyzed using the Affymet...
متن کاملSudden suffocation with cancer of unknown primary: a case report and review of diagnostic approach.
A case of a 31-year-old woman with sudden respiratory distress is presented. Preliminary evaluations and imaging studies did not reveal the underlying cause. Workup during hospital stay showed advanced metastatic cancer of unknown primary origin. This is an unusual presentation of cancer of an unknown primary involving the thyroid with sudden suffocation. It suggests that malignancies involving...
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ژورنال
عنوان ژورنال: Cancer
سال: 2004
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.20202